Immunohistological evaluation of proprioceptive potential of the residual stump of injured anterior cruciate ligaments (ACL)

被引:138
作者
Dhillon, Mandeep S. [1 ]
Bali, Kamal [1 ]
Vasistha, R. K. [2 ]
机构
[1] Postgrad Inst Med Educ & Res, Dept Orthopaed, Chandigarh 160012, India
[2] Postgrad Inst Med Educ & Res, Dept Histopathol, Chandigarh 160012, India
关键词
PATELLAR TENDON; RECONSTRUCTION; MECHANORECEPTORS; GRAFT; REPLACEMENT; MOTION; JOINT;
D O I
10.1007/s00264-009-0948-1
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
100224 [整形外科学];
摘要
To evaluate proprioceptive potential in residual remnants, tissue harvested from ruptured ACLs in 63 consecutive patients was examined for evidence of residual proprioceptive fibres using H&E, and monoclonal antibodies to S-100 and NFP (neurofilament protein). Histological examination showed good subsynovial and intra-fascicular vascularity with free nerve endings in the majority. Morphologically normal mechanoreceptors (H&E) and proprioceptive fibres (positivity with monoclonal antibody for NFP) were found in 46% and 52.4% of stumps, respectively. A statistically significant correlation between injury duration and persistence of mechanoreceptors and proprioceptive fibres was noted. More fibres were seen where ACL remnant was adherent to PCL. Our study has shown that persistent residual proprioceptive fibres in injured ACLs (especially early cases with PCL adherence) are significant; not shaving ACL remnants may be of potential benefit during ACL reconstruction, as some re-innervation and recovery of proprioceptive potential may be possible, thus improving clinical outcomes.
引用
收藏
页码:737 / 741
页数:5
相关论文
共 21 条
[1]
ANTERIOR CRUCIATE LIGAMENT REPLACEMENT USING PATELLAR TENDON - AN EVALUATION OF GRAFT REVASCULARIZATION IN THE DOG [J].
ARNOCZKY, SP ;
TARVIN, GB ;
MARSHALL, JL .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1982, 64 (02) :217-224
[2]
PROPRIOCEPTION AND FUNCTION AFTER ANTERIOR CRUCIATE RECONSTRUCTION [J].
BARRETT, DS .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1991, 73 (05) :833-837
[3]
Bonci CM, 1999, J ATHL TRAINING, V34, P155
[4]
The effects of joint position and direction of joint motion on proprioceptive sensibility in anterior cruciate ligament-deficient athletes [J].
Borsa, PA ;
Lephart, SM ;
Irrgang, JJ ;
Safran, MR ;
Fu, FH .
AMERICAN JOURNAL OF SPORTS MEDICINE, 1997, 25 (03) :336-340
[5]
Immunohistochemical analysis of mechanoreceptors in the human posterior cruciate ligament - A demonstration of its proprioceptive role and clinical relevance [J].
Del Valle, ME ;
Harwin, SF ;
Maestro, A ;
Murcia, A ;
Vega, JA .
JOURNAL OF ARTHROPLASTY, 1998, 13 (08) :916-922
[6]
DENTI M, 1994, CLIN ORTHOP RELAT R, P29
[7]
Fromm B, 1994, Knee Surg Sports Traumatol Arthrosc, V2, P118, DOI 10.1007/BF01476484
[8]
The presence of proprioceptive mechanoreceptors in the remnants of the ruptured ACL as a possible source of re-innervation of the ACL autograft [J].
Georgoulis, AD ;
Pappa, L ;
Moebius, U ;
Malamou-Mitsi, V ;
Pappa, S ;
Papageorgiou, CO ;
Agnantis, NJ ;
Soucacos, PN .
KNEE SURGERY SPORTS TRAUMATOLOGY ARTHROSCOPY, 2001, 9 (06) :364-368
[9]
JOHANSSON H, 1991, CRIT REV BIOMED ENG, V18, P341
[10]
JOHANSSON H, 1991, CLIN ORTHOP RELAT R, V268, P161