Haemolymph proteins of larvae of Galleria mellonella detoxify endotoxins of the insect pathogenic bacteria Xenorhabdus nematophilus (Enterobacteriaceae)

被引：66

作者：

Dunphy, G ^{[1
]}

Halwani, A ^{[1
]}

机构：

[1] McGill Univ, Dept Nat Resource Sci, St Anne De Bellevue, PQ H9X 3V9, Canada

来源：

JOURNAL OF INSECT PHYSIOLOGY | 1997年 / 43卷 / 11期

关键词：

Galleria; haemolymph; proteins; Xenorhabdus; endotoxins;

D O I：

10.1016/S0022-1910(97)00072-3

中图分类号：

Q96 [昆虫学];

学科分类号：

摘要：

Haemolymph of non-vaccinated Galleria mellonella larvae contains two proteins, LBP-1 (17.2 kDa) and LBP-2 (26.0 kDa) that: 1. bond to the surfaces of the insect pathogenic bacteria, Xenorhabdus nematophilus; 2. prevented lipid A-binding dye attaching to the lipid A of X. nematophilus endotoxin; and 3. reduced endotoxin activity on the haemocytes. Protein LBP-1 also blocked the inhibition of prophenoloxidase activation by the endotoxins. It is proposed that proteins LBP-1 and LBP-2 are part of the containment responses of the insects to bacteria. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：1023 / 1029

页数：7

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