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Rocks: Multifunctional kinases in cell behaviour

被引：1605
作者：
Riento, K
Ridley, AJ
机构：
[1] UCL Royal Free & Univ Coll, Ludwig Inst Canc Res, Sch Med, London W1W 7BS, England
[2] UCL, Dept Biochem & Mol Biol, London WC1E 6BT, England
来源：
NATURE REVIEWS MOLECULAR CELL BIOLOGY | 2003年 / 4卷 / 06期
关键词：
D O I：
10.1038/nrm1128
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
ROCKs, or Rho kinases, are serine/threonine kinases that are involved in many aspects of cell motility, from smooth-muscle contraction to cell migration and neurite outgrowth. Recent experiments have defined new functions of ROCKs in cells, including centrosome positioning and cell-size regulation, which might contribute to various physiological and pathological states.
引用
收藏
页码：446 / 456
页数：11
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