Two new similar alkaloids from Portulaca oleracea L.

被引：31

作者：

Li, Cuiyu ^{[1
]}

Ying, Zheming ^{[2
]}

Gao, Mingzhe ^{[3
]}

Wei, Wenjuan ^{[4
]}

Hao, Dong ^{[1
]}

Xu, Liang ^{[1
]}

Tao, Xiaojun ^{[1
]}

Zhang, Wenjie ^{[1
]}

Ying, Xixiang ^{[1
]}

Liu, Jing ^{[4
]}

机构：

[1] Liaoning Univ Tradit Chinese Med, Sch Pharm, Dalian, Peoples R China

[2] Liaoning Univ Tradit Chinese Med, Sch Clin 1, Shenyang, Peoples R China

[3] Chinese Acad Sci, Dalian Inst Chem Phys, Dalian, Peoples R China

[4] Dalian Med Univ, Regenerat Med Ctr, Affiliated Hosp 1, Dalian, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2017年 / 31卷 / 15期

基金：

国家高技术研究发展计划(863计划); 中国国家自然科学基金;

关键词：

Portulaca oleracea L; alkaloids; NMR; cytotoxicity; CELLS;

D O I：

10.1080/14786419.2017.1292507

中图分类号：

O69 [应用化学];

学科分类号：

070301 [无机化学];

摘要：

Two novel alkaloids named oleraciamide A (1) and oleraciamide B (2) were isolated from Portulaca oleracea L., and spectroscopic methods including 1D and 2D nuclear magnetic resonance and high-resolution electrospray ionisation quadrupole-time of flight mass spectrometer spectrometry techniques are employed to determine their structures. Oleraciamide A (1) was evaluated no cytotoxicity at concentrations up to 80M over 72h against human adipose-derived stem cells (hADSCs) by CCK-8 method. [GRAPHICS] .

引用

收藏

页码：1792 / 1798

页数：7

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