Developmental Plasticity Connects Visual Cortex to Motoneurons After Stroke

被引：20

作者：

Basu, Anna ^{[1
]}

Graziadio, Sara ^{[1
]}

Smith, Martin ^{[2
]}

Clowry, Gavin J. ^{[1
]}

Cioni, Giovanni ^{[3
,4
]}

Eyre, Janet A. ^{[1
]}

机构：

[1] Newcastle Univ, Inst Neurosci, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[2] Oswestry & Birmingham Childrens Hosp, Birmingham, W Midlands, England

[3] Univ Pisa, Div Child Neurol & Psychiat, Pisa, Italy

[4] Stella Varis Sci Inst, Dept Dev Neurosci, Pisa, Italy

来源：

ANNALS OF NEUROLOGY | 2010年 / 67卷 / 01期

基金：

英国惠康基金;

关键词：

OCCIPITAL CORTEX; CEREBRAL-PALSY; MOTOR CORTEX; NEURONS; STIMULATION; PROJECTION; MONKEY; AXONS; CORD;

D O I：

10.1002/ana.21827

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We report motor cortical function in the left occipital cortex of a subject who suffered a left middle cerebral artery stroke early in development. Transcranial magnetic stimulation of the left occipital cortex evoked contraction of right hand muscles. Electroencephalogram recorded over the left occipital cortex showed: 1) coherence with electromyogram from a right hand muscle; 2) a typical sensorimotor Mu rhythm at rest that was suppressed during contraction of right hand muscles. This is the first evidence that cortical plasticity extends beyond reshaping of primary sensory cortical fields to respecification of the cortical origin of subcortically projecting pathways. ANN NEUROL 2010;67:132-136

引用

页码：132 / 136

页数：5