Spray Drying Technique. I: Hardware and Process Parameters

被引：305

作者：

Cal, Krzysztof ^{[1
]}

Sollohub, Krzysztof ^{[1
]}

机构：

[1] Med Univ Gdansk, Dept Pharmaceut Technol, PL-80416 Gdansk, Poland

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 2010年 / 99卷 / 02期

关键词：

spray drying; spray dryers; atomization; atomizers; atomizing nozzles; drying chambers; CONTAINING MICROPARTICLES; DEHUMIDIFIED AIR; TOMATO PULP; DRYER; WATER; DRUG; DISSOLUTION; PARTICLES; IMPROVE; POWDERS;

D O I：

10.1002/jps.21886

中图分类号：

R914 [药物化学];

学科分类号：

100705 [微生物与生化药学];

摘要：

Spray drying is a transformation of feed from a fluid state into a dried particulate form by spraying the feed into a hot drying medium. The main aim of drying by this method in pharmaceutical technology is to obtain dry particles with desired properties. This review presents the hardware and process parameters that affect the properties of the dried product. The atomization devices, drying chambers, air-droplet contact systems, the collection of dried product, auxiliary devices, the conduct of the spray drying process, and the significance of the individual parameters in the drying process, as well as the obtained product, are described and discussed. (C) 2009 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 99:575-586, 2010

引用

页码：575 / 586

页数：12

共 33 条

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[3]

Spray drying plants for manufacture of dustless powders - A technical note [J].