Multifocal septic arthritis and osteomyelitis caused by group A Streptococcus in a patient receiving immunomodulating therapy with etanercept

被引：32

作者：

Elwood, RL ^{[1
]}

Pelszynski, MM ^{[1
]}

Corman, LI ^{[1
]}

机构：

[1] David Grant Med Ctr, Dept Pediat, SGOC, Travis AFB, CA 94535 USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2003年 / 22卷 / 03期

关键词：

enbrel; etanercept; group A Streptococcus; juvenile rheumatoid arthritis; septic arthritis;

D O I：

10.1097/00006454-200303000-00020

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A 12-year-old girl with juvenile rheumatoid arthritis presented with signs of infection of the proximal interphalangeal joint of her left great toe 1 week after a flu-like illness. Several joints and one bone were subsequently found to be infected with group A beta-hemolytic streptococci. Despite appropriate antibiotic therapy, synovial fluid cultures remained positive for 2 weeks. We believe that the antiinflammatory medications, including etanercept (a tumor necrosis factor antagonist), used to treat this patient's arthritis contributed to the severity and unusual course of her infection.

引用

页码：286 / 288

页数：3

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