New imidazole alkaloids and zinc complexes from the Micronesian sponge Leucetta cf. chagosensis

被引：34

作者：

Fu, X

Schmitz, FJ ^{[1
]}

Tanner, RS

Kelly-Borges, M

机构：

[1] Univ Oklahoma, Dept Chem & Biochem, Norman, OK 73019 USA

[2] Univ Oklahoma, Dept Bot & Microbiol, Norman, OK 73019 USA

[3] UNITEC Inst Technol, Fac Hlth Sci & Technol, Dept Civil & Environm Engn, Auckland, New Zealand

来源：

JOURNAL OF NATURAL PRODUCTS | 1998年 / 61卷 / 03期

关键词：

D O I：

10.1021/np970453q

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Four new imidazole alkaloids, 2-5, along with the known isonaamidine B (1) were isolated from a Pacific sponge, Leucetta cf. chagosensis, collected from Yap, Federated States of Micronesia. Among these, 4 and 5 are zinc complexes derived from isonaamidine B and isonaamidine D. The structures of the new compounds were elucidated from spectral data. Isonaamidine D (3) showed weakly antifungal activity against Aspergillus niger with MIC = 100 mu g/mL.

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页码：384 / 386

页数：3

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