FDG uptake, tumour characteristics and response to therapy: A review

被引：153

作者：

Smith, TAD ^{[1
]}

机构：

[1] Royal Marsden NHS Trust, Dept Nucl Med, Surrey SM2 5PT, England

来源：

NUCLEAR MEDICINE COMMUNICATIONS | 1998年 / 19卷 / 02期

关键词：

D O I：

10.1097/00006231-199802000-00002

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The use of FDG-PET imaging in tumour detection is now well established. Many studies have suggested that changes in the uptake of FDG predict tumour response to therapy and that further clinical information regarding tumour grade and proliferative status may also be derived from FDG-uptake scans. More studies are required to verify the role of FDG-PET in patient management. Upregulation of hexokinase and glucose transporters, especially Glut-1, and downregulation of glucose-6-phosphatase are frequently associated with transformation. The extent of these changes has been related to both differentiation and proliferation largely corresponding with FDG-uptake studies.

引用

页码：97 / 105

页数：9

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