In search of endocrine progenitor/stem cells in the human pancreas

被引:9
作者
Hayek, A [1 ]
机构
[1] UCSD Sch Med, Dept Pediat, Whittier Inst Diabet, Islet Res Lab, La Jolla, CA 92037 USA
关键词
differentiation; fetal pancreas; precursor cell;
D O I
10.1111/j.1399-543X.2004.00081.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Motives to isolate endocrine precursor cells vary between clinical and basic research needs. In our case, the object has been to identify cell populations that could be used for cell replacement in situations of beta-cell deficiency, such as type 1 diabetes. Initially, as was the case with most laboratories oriented toward translational islet research, experimentation was geared more toward cell replication than to the identification and isolation of putative endocrine cell precursors.
引用
收藏
页码:70 / 74
页数:5
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