Novel cationic titanium(IV) Lewis acids and their use in asymmetric aldol reactions

被引：34

作者：

Ishimaru, K ^{[1
]}

Monda, K ^{[1
]}

Yamamoto, Y ^{[1
]}

Akiba, K ^{[1
]}

机构：

[1] Hiroshima Univ, Fac Sci, Dept Chem, Higashihiroshima 739, Japan

来源：

TETRAHEDRON | 1998年 / 54卷 / 5-6期

关键词：

D O I：

10.1016/S0040-4020(97)10296-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Novel cationic Lewis acids were generated by the addition of silver hexafluoroantimonate to titanium complexes 7 (TiCl4 .(R,R)-1,2-diphenylethane-1,2-diol dialkyl ether) or 8 (TiCl3(OR).(R,R)-1,2-diphenylethane-1,2-diol dialkyl ether) at -20 degrees C. Interestingly, the titanium complexes 7 or 8 could be isolated and the structures of 7c (TiCl4 .(R,R)-1,2-diphenylethane-1,2-diol di-n-propyl ether) and 8a (TiCl3(O-i-Pr).(R,R)-1,2-diphenylethane-1,2-diol dimethyl ether) were determined by X-ray analysis. Asymmetric aldol reaction using the cationic Lewis acids is also described. (C) 1997 Elsevier Science Ltd. All rights reserved.

引用

页码：727 / 734

页数：8

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