Peri- and intra-operative management of the goat during acute surgical experimentation

被引:9
作者
Flaherty, Devin C. [3 ,4 ]
Hoxha, Besim [4 ,5 ]
Nelson, Shirley [1 ]
Sun, Jie [3 ]
Gurji, Hunaid [3 ,4 ]
Simecka, Jerry W. [2 ]
Mallet, Robert T. [3 ,4 ,5 ]
Olivencia-Yurvati, Albert H. [3 ,4 ,5 ]
Daniels, Egeenee Q. [1 ]
机构
[1] Univ N Texas, Hlth Sci Ctr, Dept Lab Anim Med, Ft Worth, TX 76107 USA
[2] Univ N Texas, Hlth Sci Ctr, Dept Mol Biol & Immunol, Ft Worth, TX USA
[3] Univ N Texas, Hlth Sci Ctr, Dept Integrat Physiol, Ft Worth, TX USA
[4] Univ N Texas, Hlth Sci Ctr, Dept Surg, Ft Worth, TX USA
[5] Univ N Texas, Hlth Sci Ctr, Cardiovasc Res Inst, Ft Worth, TX USA
关键词
Q-FEVER; DIAZEPAM-KETAMINE; PULMONARY-EDEMA; SHEEP; GUIDELINES; OUTBREAK;
D O I
10.1038/laban0310-80
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Goats are used as animal models for surgery and trauma research. The authors discuss appropriate methods for induction of anesthetics, intubation and surgical maintenance of the goat during acute experimentation. Risks imposed by the Q fever pathogen Coxiella burnetii are described, as well as measures that have proven effective in minimizing zoonotic transmission of this pathogen to laboratory personnel. With appropriate knowledge of its applications, peri- and intra-operative management and limitations, the goat is a suitable animal model for a variety of biomedical research applications.
引用
收藏
页码:80 / 85
页数:6
相关论文
共 32 条
[1]  
Afshar FS, 2005, B VET I PULAWY, V49, P481
[2]  
Allen MJ., 1999, LAB ANIMAL POCKET RE, P8
[3]   INTOXICATION BY BENZODIAZEPINES - STUDIES WITH DIAZEPAM USED AS A MODEL-COMPOUND SUGGEST AN INTERACTION WITH RED-BLOOD-CELLS CALMODULIN DEPENDENT (CA2+,MG2+) ATPASE [J].
BARRIERE, M ;
PIRIOU, A ;
TALLINEAU, C ;
BOULARD, M ;
MURA, P ;
GUETTIER, A ;
POURRAT, O .
TOXICOLOGY LETTERS, 1983, 19 (03) :287-291
[4]   Acute pulmonary edema after diazepam-ketamine in a dog [J].
Boutureira, Joseph ;
Trim, Cynthia M. ;
Cornell, Karen K. .
VETERINARY ANAESTHESIA AND ANALGESIA, 2007, 34 (05) :371-376
[5]  
BROWN MJ, 1993, AM J VET RES, V54, P1544
[6]   Haemolysis after etomidate: comparison of propylene glycol and lipid formulations [J].
Doenicke, A ;
Roizen, MF ;
Hoernecke, R ;
Mayer, M ;
Ostwald, P ;
Foss, J .
BRITISH JOURNAL OF ANAESTHESIA, 1997, 79 (03) :386-388
[7]  
Fulton LK., 1994, I LAB ANIMAL RES, V36, P557
[8]  
HAMADEH GN, 1992, J FAM PRACTICE, V35, P683
[9]   OCCUPATIONAL-HEALTH GUIDELINES FOR CONTROL OF Q-FEVER IN SHEEP RESEARCH [J].
HARRISON, RJ ;
VUGIA, DJ ;
ASCHER, MS .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1990, 590 :283-290
[10]   Natural history of Q fever in goats [J].
Hatchette, T ;
Campbell, N ;
Hudson, R ;
Raoult, D ;
Marrie, TJ .
VECTOR-BORNE AND ZOONOTIC DISEASES, 2003, 3 (01) :11-15