Ocular biomechanics and biotransport

被引:212
作者
Ethier, CR [1 ]
Johnson, M
Ruberti, J
机构
[1] Univ Toronto, Dept Mech & Ind Engn, Toronto, ON M5S 3G8, Canada
[2] Univ Toronto, Dept Ophthalmol, Toronto, ON M5S 3G8, Canada
[3] Univ Toronto, Inst Biomat & Biomed Engn, Toronto, ON M5S 3G8, Canada
[4] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
[5] Cambridge Polymer Grp Inc, Somerville, MA 02143 USA
[6] Schepens Eye Res Inst, Boston, MA 02114 USA
关键词
cornea; glaucoma; aqueous humor drainage; optic nerve head; Bruch's membrane;
D O I
10.1146/annurev.bioeng.6.040803.140055
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
The eye transduces light, and we usually do not think of it as a biomechanical structure. Yet it is actually a pressurized, thick-walled shell that has an internal and external musculature, a remarkably complex internal vascular system, dedicated fluid production and drainage tissues, and a variety of specialized fluid and solute transport systems. Biomechanics is particularly involved in accommodation (focusing near and far), as well as in common disorders such as glaucoma, macular degeneration, myopia, and presbyopia. In this review, we give a (necessarily brief) overview of many of the interesting biomechanical aspects of the eye, concluding with a list of open problems.
引用
收藏
页码:249 / 273
页数:27
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