Synthesis and reactivity of [18F]-N-fluorobenzenesulfonimide

被引：84

作者：

Teare, Harriet

Robins, Edward G.

Arstad, Erik

Luthra, Sajinder K.

Gouverneur, Veronique

机构：

[1] Hammersmith Hosp, Hammersmith Imanet Ltd, London W12 0NN, England

[2] Univ Oxford, Chem Res Lab, Oxford OX1 3TA, England

来源：

CHEMICAL COMMUNICATIONS | 2007年 / 23期

关键词：

D O I：

10.1039/b701177f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel [F-18]NF reagent and two novel radiochemical transformations have been developed: [F-18]NFSi has been prepared from sodium dibenzenesulfonimide and reacted in the presence of silyl enol ethers and allylsilanes to deliver labelled fluorinated ketones and allylic fluorides respectively; the radiosynthesis of the fluorinated A ring of vitamin D-3 has also been completed with success.

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页码：2330 / 2332

页数：3

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