An efficient and stereoselective construction of the core structure of the manzamines via an intramolecular Michael reaction.

被引：21

作者：

Brands, KMJ ^{[1
]}

DiMichele, LM ^{[1
]}

机构：

[1] Merck Res Labs, Dept Proc Res, Rahway, NJ 07065 USA

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 13期

关键词：

D O I：

10.1016/S0040-4039(98)00019-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A strategically functionalized tricyclic subunit of the manzamines was efficiently synthesized with complete stereochemical control using a combination of an intramolecular Michael reaction of a pyroglutamic acid derivative and a hydrogenation. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1677 / 1680

页数：4

共 15 条

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