Absolute copy number and relative change in determinations of human immunodeficiency virus type 1 RNA in plasma: Effect of an external standard on kit comparisons

被引：37

作者：

Brambilla, D

Leung, S

Lew, J

Todd, J

Herman, S

Cronin, M

Shapiro, DE

Bremer, J

Hanson, C

Hillyer, GV

McSherry, GD

Sperling, RS

Coombs, RW

Reichelderfer, PS

机构：

[1] New England Res Inst, Watertown, MA 02172 USA

[2] NIAID, Bethesda, MD 20892 USA

[3] Chiron Corp, Emeryville, CA 94608 USA

[4] Roche Mol Syst, Branchburg, NJ 08876 USA

[5] Organon Teknika Corp, Durham, NC 27712 USA

[6] Harvard Univ, Sch Publ Hlth, Boston, MA 02115 USA

[7] Rush Presbyterian St Lukes Med Ctr, Chicago, IL 60612 USA

[8] Baylor Coll Med, Houston, TX 77030 USA

[9] Univ Puerto Rico, Sch Med, San Juan, PR 00936 USA

[10] Univ Med & Dent New Jersey, New Jersey Med Sch, Newark, NJ 07103 USA

[11] Mt Sinai Med Ctr, New York, NY 10029 USA

[12] Univ Washington, Seattle, WA 98195 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1998年 / 36卷 / 01期

关键词：

D O I：

10.1128/JCM.36.1.311-314.1998

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Use of a common set of human immunodeficiency virus type 1 (HIV-1) RNA standards eliminated differences among absolute HIV-1 RNA copy number estimates made with three commercially available assays. The relative changes in the viral RNA levels determined by the commercial assays were similar and were unaffected by the use of a common set of standards.

引用

页码：311 / 314

页数：4

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