The prothrombin gene 3′-untranslated region mutation is frequently associated with factor V Leiden in thrombophilic patients and shows ethnic-specific variation in allele frequency

被引：34

作者：

Howard, TE ^{[1
]}

Marusa, M ^{[1
]}

Boisza, J ^{[1
]}

Young, A ^{[1
]}

Sequeira, J ^{[1
]}

Channell, C ^{[1
]}

Guy, C ^{[1
]}

Benson, E ^{[1
]}

Duncan, A ^{[1
]}

机构：

[1] Emory Univ Hosp, Dept Pathol & Lab Med, Atlanta, GA 30322 USA

来源：

BLOOD | 1998年 / 91卷 / 03期

关键词：

D O I：

10.1182/blood.V91.3.1092.1092_1092_1093

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：1092 / 1092

页数：1

共 6 条

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[2]

FERRARESI P, 1997, THROMB HAEMOSTASIS, V77, P379

[3] A patient homozygous for a mutation in the prothrombin gene 3'-untranslated region associated with massive thrombosis [J].

Howard, TE ;

Marusa, M ;

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Duncan, A .

BLOOD COAGULATION & FIBRINOLYSIS, 1997, 8 (05) :316-319

[4]

POORT RS, 1996, BLOOD, V88, P3699

[5] Ethnic distribution of factor V Leiden in 4047 men and women - Implications for venous thromboembolism screening [J].

Ridker, PM ;

Miletich, JP ;

Hennekens, CH ;

Buring, JE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1997, 277 (16) :1305-1307

[6] A common prothrombin variant (20210 G to A) increases the risk of myocardial infarction in young women [J].

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Psaty, BM ;

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Vos, HL .

BLOOD, 1997, 90 (05) :1747-1750

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