The role of the ribosome-translocon complex in translation and assembly of polytopic membrane proteins

被引：39

作者：

Bibi, E ^{[1
]}

机构：

[1] Weizmann Inst Sci, Dept Biochem, IL-76100 Rehovot, Israel

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1998年 / 23卷 / 02期

关键词：

D O I：

10.1016/S0968-0004(97)01134-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Newly synthesized polytopic membrane proteins and secretory proteins often share the same target membrane as their primary destination, and in some cases, the cellular machinery that targets and transfers them into or across the membrane. Unlike secretory proteins, which are localized to the external compartment, each polytopic membrane protein molecule must be partitioned among the cytoplasm, the membrane and the external milieu. How does the ribosome-translocon complex cope with the different domains of polytopic membrane proteins?

引用

页码：51 / 55

页数：5

共 40 条

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