Model studies indicate that copper phenanthroline induces direct strand breaks via β-elimination of the 2′-deoxyribonolactone intermediate observed in enediyne mediated DNA damage

被引:68
作者
Chen, TQ [1 ]
Greenberg, MM [1 ]
机构
[1] Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA
关键词
D O I
10.1021/ja9800075
中图分类号
O6 [化学];
学科分类号
0703 ;
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页码:3815 / 3816
页数:2
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