The development of hydrazide gamma-turn mimetics

被引：12

作者：

Ferguson, MD

Meara, JP

Nakanishi, H

Lee, MS

Kahn, M

机构：

[1] MOLECUMET LTD,BELLEVUE,WA 98005

[2] UNIV WASHINGTON,DEPT PATHOBIOL,SEATTLE,WA 98195

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 40期

关键词：

D O I：

10.1016/S0040-4039(97)01664-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Monte Carlo calculations show a classical gamma-turn in a family of metabolites known as the malformins. This led to the synthesis of epimeric seven-membered ring gamma-turn mimetics starting from leucine. NMR temperature coefficient studies were also performed. (C) 1997 Elsevier Science Ltd.

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收藏

页码：6961 / 6964

页数：4

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