Cyclooxygenase-2 inhibitors and atherosclerosis

被引:13
作者
Belton, O [1 ]
Fitzgerald, D [1 ]
机构
[1] Royal Coll Surgeons Ireland, Inst Biopharmaceut Sci, Dublin 2, Ireland
关键词
D O I
10.1016/S0735-1097(03)00305-X
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1820 / 1822
页数:3
相关论文
共 42 条
[1]  
Belton O, 2000, CIRCULATION, V102, P840
[2]   Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. [J].
Bombardier, C ;
Laine, L ;
Reicin, A ;
Shapiro, D ;
Burgos-Vargas, R ;
Davis, B ;
Day, R ;
Ferraz, MB ;
Hawkey, CJ ;
Hochberg, MC ;
Kvien, TK ;
Schnitzer, TJ ;
Weaver, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (21) :1520-1528
[3]   Prostanoid receptors: Subtypes and signaling [J].
Breyer, RM ;
Bagdassarian, CK ;
Myers, SA ;
Breyer, MD .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2001, 41 :661-690
[4]   Arachidonic acid is preferentially metabolized by cyclooxygenase-2 to prostacyclin and prostaglandin E2 [J].
Brock, TG ;
McNish, RW ;
Peters-Golden, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (17) :11660-11666
[5]   Cyclooxygenase-2 promotes early atherosclerotic lesion formation in LDL receptor-deficient mice [J].
Burleigh, ME ;
Babaev, VR ;
Oates, JA ;
Harris, RC ;
Gautam, S ;
Riendeau, D ;
Marnett, LJ ;
Morrow, JD ;
Fazio, S ;
Linton, MF .
CIRCULATION, 2002, 105 (15) :1816-1823
[6]   Roles of cyclooxygenase (COX)-1 and COX-2 in prostanoid production by human endothelial cells: Selective up-regulation of prostacyclin synthesis by COX-2 [J].
Caughey, GE ;
Cleland, LG ;
Penglis, PS ;
Gamble, JR ;
James, MJ .
JOURNAL OF IMMUNOLOGY, 2001, 167 (05) :2831-2838
[7]   15-deoxy-Δ 12,14-prostaglandin J2 inhibition of NF-κB-DNA binding through covalent modification of the p50 subunit [J].
Cernuda-Morollón, E ;
Pineda-Molina, E ;
Cañada, FJ ;
Pérez-Sala, D .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (38) :35530-35536
[8]   Role of prostacyclin in the cardiovascular response to thromboxane A2 [J].
Cheng, Y ;
Austin, SC ;
Rocca, B ;
Koller, BH ;
Coffman, TM ;
Grosser, T ;
Lawson, JA ;
FitzGerald, GA .
SCIENCE, 2002, 296 (5567) :539-541
[9]  
Chinery R, 1999, CANCER RES, V59, P2739
[10]   Overexpression of functionally coupled cyclooxygenase-2 and prostaglandin E synthase in symptomatic atherosclerotic plaques as a basis of prostaglandin E2-dependent plaque instability [J].
Cipollone, F ;
Prontera, C ;
Pini, B ;
Marini, M ;
Fazia, M ;
De Cesare, D ;
Iezzi, A ;
Ucchino, S ;
Boccoli, G ;
Saba, V ;
Chiarelli, F ;
Cuccurullo, F ;
Mezzetti, A .
CIRCULATION, 2001, 104 (08) :921-927