Voltage-gated potassium channels in cell proliferation

被引:255
作者
Pardo, LA [1 ]
机构
[1] Max Planck Inst Expt Med, D-37075 Gottingen, Germany
关键词
D O I
10.1152/physiol.00011.2004
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
It is commonly accepted that cells require K+ channels to proliferate, The role(s) of K+ channels in the process is, however, poorly understood. Cloning of K+ channel genes opened the possibility to approach this problem in a way more independent from pharmacological tools. Recent work shows that several identified K+ channels are important in both physiological and pathological cell proliferation and open a promising pathway for novel targeted therapies.
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页码:285 / 292
页数:8
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