Decarbonylation of tetrasubstituted barbituric acids as a versatile method for preparation of N,N′,2,2-tetrasubstituted malonamides

被引：13

作者：

Jursic, BS ^{[1
]}

机构：

[1] Univ New Orleans, Dept Chem, New Orleans, LA 70148 USA

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 28期

关键词：

2,3,4(1H,3H,5H)pyrimidinetriones (barbituric acids); 1,3,5,5-tetrasubstituted-barbituric acid; N,N ',2,2-tetrasubstituted-malonamides; malonamides;

D O I：

10.1016/S0040-4039(00)00852-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A procedure for the preparation of 1,3,5,5-tetrasubstituted-2,3,4(1H,3H, SH)pyrimidinetriones (barbituric acids) through alkylation of the less substituted 2,3,4(1H,3H,5H)pyfimidinetriones (barbituric acids) and decarbonylation of the tetrasubstituted product into the N,Nl,2,2-tetrasubstituted-manlonamides are described. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：5325 / 5328

页数：4

共 11 条

[1] CHAN GYS, 1997, J CHEM SOC DA, P647
[2] Darling C. M., 1985, US Pat., Patent No. [4 537 781, 4537781]
[3] N-benzylamides as derivatives for identifying the acyl group in esters
Dermer, OC
King, J
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1943, 8 (02) : 168 - 173
[4] DRALING, 1979, J PHARM SCI, V69, P108
[5] HIGHLY SELECTIVE SOLVENT-EXTRACTION OF COPPER(II) FROM TRANSITION-METAL IONS WITH DIBUTYL N,N'-BIS(8-QUINOLYL)MALONAMIDE
HIRATANI, K
TAGUCHI, K
OHHASHI, K
NAKAYAMA, H
[J]. CHEMISTRY LETTERS, 1989, (11) : 2073 - 2076
[6] HIRATANI K, 1991, Patent No. 5071989
[7] Structural studies of lanthanide complexes with new hydrophobic malonamide solvent extraction agents
Iveson, PB
Drew, MGB
Hudson, MJ
Madic, C
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1999, (20): : 3605 - 3610
[8] MARCH J, 1992, ADV ORG CHEM, P732
[9] Uptake of metal ions by extraction chromatography using dimethyl dibutyl tetradecyl-1,3-malonamide (DMDBTDMA) as the stationary phase
Mohapatra, P
Sriram, S
Manchanda, V
Badheka, L
[J]. SEPARATION SCIENCE AND TECHNOLOGY, 2000, 35 (01) : 39 - 55
[10] PATEL, 1961, J SCI IND RES B, V20, P457

← 1 2 →