Coupling between vesicle shape and the non-homogeneous lateral distribution of membrane constituents in Golgi bodies

被引：19

作者：

Iglic, A

Fosnaric, M

Hägerstrand, H

Kralj-Iglic, V

机构：

[1] Univ Ljubljana, Fac Elect Engn, Appl Phys Lab, SI-1000 Ljubljana, Slovenia

[2] Abo Akad Univ, Dept Biol, BIOCITY, FIN-20520 Turku, Finland

[3] Univ Ljubljana Fac Med, Inst Biophys, SI-1000 Ljubljana, Slovenia

来源：

FEBS LETTERS | 2004年 / 574卷 / 1-3期

关键词：

Golgi body; non-homogenenous lateral distribution; anisotropic membrane component; vesicle shape; rafts;

D O I：

10.1016/j.febslet.2004.07.085

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this work, a hypothesis is presented that could explain the non-homogeneous lateral distribution of membrane components in Golgi vesicles. It is shown that the non-homogeneous lateral distribution of membrane components and the specific flattened shape of Golgi vesicles are strongly coupled. In agreement with experimental evidence, it is indicated that some of the membrane components may be concentrated mainly on the curved bulbous rims of the Golgi vesicles, while the other components are distributed predominantly in their flat central part. (C) 2004 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

引用

页码：9 / 12

页数：4

共 26 条

[1] Evidence for segregation of sphingomyelin and cholesterol during formation of COPI-coated vesicles [J].