Epidemiology of influenza-like illness in the Amazon Basin of Peru, 2008-2009

被引:20
作者
Forshey, Brett M. [1 ]
Laguna-Torres, Victor A. [1 ]
Vilcarromero, Stalin [1 ]
Bazan, Isabel [1 ]
Rocha, Claudio [1 ]
Morrison, Amy C. [1 ,2 ]
Stoddard, Steven T. [2 ]
Alegre, Yuri [3 ]
Gomez, Jorge [4 ]
Scott, Thomas W. [2 ]
Kochel, Tadeusz J. [1 ]
机构
[1] US Naval Med Res Ctr Detachment, Lima, Peru
[2] Univ Calif Davis, Dept Entomol, Davis, CA 95616 USA
[3] DRESA Loreto, Iquitos, Peru
[4] Minist Salud Peru, Lima, Peru
关键词
Amazon; cohort; Influenza; Peru; AIR-POLLUTION; TRANSMISSION; SEASONALITY; SURVEILLANCE; BURDEN; VIRUS;
D O I
10.1111/j.1750-2659.2010.00139.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background Data addressing the incidence and epidemiology of influenza and influenza-like illness (ILI) in tropical regions of the world is scarce, particularly for the neotropics of South America. Methods We conducted active, population-based surveillance for ILI across 45 city blocks within the Amazon Basin city of Iquitos, Peru. Demographic data and household characteristics were collected for all participants, and participating households were visited three times weekly to inquire about ILI (fever plus cough or sore throat) among household residents. Nasal and oropharyngeal swabs were collected from participants with ILI and tested for influenza virus infection. Results Between May 1, 2008 and July 8, 2009, we monitored 10,341 participants for ILI for a total of 11 569 center dot 5 person-years. We detected 459 ILI episodes, with 252 (54 center dot 9%) of the participants providing specimens. Age-adjusted incidence of ILI was estimated to be 46 center dot 7 episodes/1000 person-years. Influenza A and B viruses were detected in 25 (9 center dot 9%) and 62 (24 center dot 6%) specimens of ILI patients, respectively, for an estimated age-adjusted incidence rate of 16 center dot 5 symptomatic influenza virus infections/1000 person-years. Risk factors for ILI included age, household crowding, and use of wood as cooking fuel. For influenza virus infection specifically, age and use of wood as a cooking fuel were also identified as risk factors, but no effect of household crowding was observed. Conclusions Our results represent the initial population-based description of the epidemiology of ILI in the Amazon region of Peru, which will be useful for developing region-specific strategies for reducing the burden of respiratory disease.
引用
收藏
页码:235 / 243
页数:9
相关论文
共 30 条
[1]   Influenza-Like Illness Sentinel Surveillance in Peru [J].
Alberto Laguna-Torres, V. ;
Gomez, Jorge ;
Ocana, Victor ;
Aguilar, Patricia ;
Saldarriaga, Tatiana ;
Chavez, Edward ;
Perez, Juan ;
Zamalloa, Hernan ;
Forshey, Brett ;
Paz, Irmia ;
Gomez, Elizabeth ;
Ore, Roel ;
Chauca, Gloria ;
Ortiz, Ernesto ;
Villaran, Manuel ;
Vilcarromero, Stalin ;
Rocha, Claudio ;
Chincha, Omayra ;
Jimenez, Gerardo ;
Villanueva, Miguel ;
Pozo, Edwar ;
Aspajo, Jackeline ;
Kochel, Tadeusz .
PLOS ONE, 2009, 4 (07)
[2]   Seasonality of influenza in Brazil: A traveling wave from the Amazon to the subtropics [J].
Alonso, Wladimir J. ;
Viboud, Cecile ;
Simonsen, Lone ;
Hirano, Eduardo W. ;
Daufenbach, Luciane Z. ;
Miller, Mark A. .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 2007, 165 (12) :1434-1442
[3]  
[Anonymous], 2008, CENS NAC 2007 11 POB
[4]   Pandemic influenza planning in the United States from a health disparities perspective [J].
Blumenshine, Philip ;
Reingold, Arthur ;
Egerter, Susan ;
Mockenhaupt, Robin ;
Braveman, Paula ;
Marks, James .
EMERGING INFECTIOUS DISEASES, 2008, 14 (05) :709-715
[5]  
*CDC, 2009, INFL DIS
[6]   Air pollution and infection in respiratory illness [J].
Chauhan, AJ ;
Johnston, SL .
BRITISH MEDICAL BULLETIN, 2003, 68 :95-112
[7]   Seasonal trends of viral respiratory tract infections in the tropics [J].
Chew, FT ;
Doraisingham, S ;
Ling, AE ;
Kumarasinghe, G ;
Lee, BW .
EPIDEMIOLOGY AND INFECTION, 1998, 121 (01) :121-128
[8]  
Clague Birgit, 2006, Southeast Asian Journal of Tropical Medicine and Public Health, V37, P488
[9]   Preliminary Findings of a Randomized Trial of Non-Pharmaceutical Interventions to Prevent Influenza Transmission in Households [J].
Cowling, Benjamin J. ;
Fung, Rita O. P. ;
Cheng, Calvin K. Y. ;
Fang, Vicky J. ;
Chan, Kwok Hung ;
Seto, Wing Hong ;
Yung, Raymond ;
Chiu, Billy ;
Lee, Paco ;
Uyeki, Timothy M. ;
Houck, Peter M. ;
Peiris, J. S. Malik ;
Leung, Gabriel M. .
PLOS ONE, 2008, 3 (05)
[10]   The health impacts of exposure to indoor air pollution from solid fuels in developing countries: Knowledge, gaps, and data needs [J].
Ezzati, M ;
Kammen, DM .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2002, 110 (11) :1057-1068