Usefulness of urinary antigen detection by an immunochromatographic test for diagnosis of pneumococcal pneumonia in children

被引:69
作者
Domínguez, J
Blanco, S
Rodrigo, C
Azuara, M
Galí, N
Mainou, A
Esteve, A
Castellví, A
Prat, C
Matas, L
Ausina, V
机构
[1] Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, Microbiol Serv, Badalona 08916, Barcelona, Spain
[2] Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, Serv Pediat, Badalona 08916, Barcelona, Spain
[3] Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, Ctr Estudis Epidemiol Sobre SIDA Catalunya, CEESCAT, Badalona 08916, Barcelona, Spain
[4] Univ Autonoma Barcelona, Hosp Univ Germans Trias i Pujol, Serv Cirugia Pediat, Badalona 08916, Barcelona, Spain
关键词
D O I
10.1128/JCM.41.5.2161-2163.2003
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We evaluated an immunochromatographic assay detecting pneumococcal antigen in urine samples from children diagnosed with pneumococcal pneumonia. The sensitivity and specificity of the immunochromatographic test with nonconcentrated urine (NCU) were 86.7 and 62.9%, respectively; with concentrated urine (CU), they were 100 and 11.7%, respectively. Pneumococcal antigen was also detected in 42.5% of NCU and 87.1% of CU samples from nasopharyngeal carriers. This is a nonspecific test for the diagnosis of pneumococcal pneumonia in children, particularly the very young.
引用
收藏
页码:2161 / 2163
页数:3
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