Dissolving biomolecules and modifying biomedical implants with supercritical carbon dioxide

被引：16

作者：

Webb, PB ^{[1
]}

Marr, PC ^{[1
]}

Parsons, AJ ^{[1
]}

Gidda, HS ^{[1
]}

Howdle, SM ^{[1
]}

机构：

[1] Univ Nottingham, Sch Chem, Nottingham NG7 2RD, England

来源：

PURE AND APPLIED CHEMISTRY | 2000年 / 72卷 / 07期

关键词：

D O I：

10.1351/pac200072071347

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We describe two methodologies for dissolving ionic/polar species in scCO(2). Both lead to a broadening of the range of applications for scCO(2). Fluorinated surfactants may be used to prepare water in carbon dioxide microemulsions to allow solubilization of ionic and biological species. We outline also the preparation of scCO(2) soluble metal precursors that can be impregnated efficiently into polymeric substrates. Further processing by heat or UV light leads to metallic particles distributed throughout a polymer substrate. The clean synthesis of such composites can be applied to the development of improved medical implants.

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收藏

页码：1347 / 1355

页数：9

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