Sleep homeostasis in infant rats

被引:15
作者
Blumberg, MS [1 ]
Middlemis-Brown, JE [1 ]
Johnson, ED [1 ]
机构
[1] Univ Iowa, Dept Psychol, Program Behav & Cognit Neurosci, Iowa City, IA 52242 USA
关键词
D O I
10.1037/0735-7044.118.6.1253
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Homeostatic regulation is a defining characteristic of sleep but has rarely been examined in infants. This study presents an automated method of sleep deprivation in which 5-day-old rats were shocked whenever the nuchal muscle became atonic. The intensity of shock was always set at the minimal level required to maintain arousal. Deprived pups exhibited rapid increases in sleep pressure, as evidenced by increased attempts to enter sleep and subsequent increases in sensory threshold; this increased sensory threshold was not due to sensory adaptation of peripheral receptors. In addition, myoclonic twitching was suppressed during the 30-min deprivation period, leading to rebound twitching during recovery sleep. These results provide the earliest demonstration of the homeostatic regulation of sleep in an altricial mammal.
引用
收藏
页码:1253 / 1261
页数:9
相关论文
共 47 条
[1]  
[Anonymous], PRINCIPLES PRACTICE
[2]  
[Anonymous], ANIMAL INTELLIGENCE
[3]  
Berger RJ, 1966, PSYCHOPHYSIOLOGY, V2, P354
[4]   DUAL MECHANISMS OF TWITCHING DURING SLEEP IN NEONATAL RATS [J].
BLUMBERG, MS ;
LUCAS, DE .
BEHAVIORAL NEUROSCIENCE, 1994, 108 (06) :1196-1202
[5]  
Blumberg MS, 1996, DEV PSYCHOBIOL, V29, P1, DOI 10.1002/(SICI)1098-2302(199601)29:1<1::AID-DEV1>3.0.CO
[6]  
2-Y
[7]   Thermogenesis, myoclonic twitching, and ultrasonic vocalization in neonatal rats during moderate and extreme cold exposure [J].
Blumberg, MS ;
Stolba, MA .
BEHAVIORAL NEUROSCIENCE, 1996, 110 (02) :305-314
[8]   ANIMAL SLEEP - A REVIEW OF SLEEP DURATION ACROSS PHYLOGENY [J].
CAMPBELL, SS ;
TOBLER, I .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 1984, 8 (03) :269-300
[9]   THE ATONIA AND MYOCLONIA OF ACTIVE (REM) SLEEP [J].
CHASE, MH ;
MORALES, FR .
ANNUAL REVIEW OF PSYCHOLOGY, 1990, 41 :557-584
[10]  
Corner M A, 1980, Prog Brain Res, V53, P347, DOI 10.1016/S0079-6123(08)60074-6