Pilomatricomas contain activating mutations in β-catenin

被引：16

作者：

Chan, EF ^{[1
]}

机构：

[1] Univ Penn, Med Ctr, Dept Dermatol, Philadelphia, PA 19104 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2000年 / 43卷 / 04期

关键词：

D O I：

10.1067/mjd.2000.109275a

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

引用

页码：701 / 702

页数：2

共 10 条

[1] beta-catenin is a target for the ubiquitin-proteasome pathway [J].

Aberle, H ;

Bauer, A ;

Stappert, J ;

Kispert, A ;

Kemler, R .

EMBO JOURNAL, 1997, 16 (13) :3797-3804

[2] Functional interaction of beta-catenin with the transcription factor LEF-1 [J].

Behrens, J ;

vonKries, JP ;

Kuhl, M ;

Bruhn, L ;

Wedlich, D ;

Grosschedl, R ;

Birchmeier, W .

NATURE, 1996, 382 (6592) :638-642

[3] A common human skin tumour is caused by activating mutations in β-catenin [J].

Chan, EF ;

Gat, U ;

McNiff, JM ;

Fuchs, E .

NATURE GENETICS, 1999, 21 (04) :410-413

[4] De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated β-catenin in skin [J].

Gat, U ;

DasGupta, R ;

Degenstein, L ;

Fuchs, E .

CELL, 1998, 95 (05) :605-614

[5] Lessons from hereditary colorectal cancer [J].

Kinzler, KW ;

Vogelstein, B .

CELL, 1996, 87 (02) :159-170

[6]

Miyoshi Y, 1998, CANCER RES, V58, P2524

[7] Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC [J].

Morin, PJ ;

Sparks, AB ;

Korinek, V ;

Barker, N ;

Clevers, H ;

Vogelstein, B ;

Kinzler, KW .

SCIENCE, 1997, 275 (5307) :1787-1790

[8] Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin [J].

Orford, K ;

Crockett, C ;

Jensen, JP ;

Weissman, AM ;

Byers, SW .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1997, 272 (40) :24735-24738

[9]

Sparks AB, 1998, CANCER RES, V58, P1130

[10] The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3 [J].

Yost, C ;

Torres, M ;

Miller, RR ;

Huang, E ;

Kimelman, D ;

Moon, RT .

GENES & DEVELOPMENT, 1996, 10 (12) :1443-1454

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