Missing genes in metabolic pathways: a comparative genomics approach

被引：232

作者：

Osterman, A ^{[1
]}

Overbeek, R ^{[1
]}

机构：

[1] Integrated Genomics Inc, Chicago, IL 60612 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2003年 / 7卷 / 02期

关键词：

D O I：

10.1016/S1367-5931(03)00027-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The new techniques of genome context analysis chromosomal gene clustering, protein fusions, occurrence profiles and shared regulatory sites - infer functional coupling between genes. In combination with metabolic reconstructions, these techniques can dramatically accelerate the pace of gene discovery.

引用

收藏

页码：238 / 251

页数：14

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