Spectral study and global analysis of fluorescence decays of the inclusion complexes of 2-amino-4,6-dimethyl pyrimidine with α- and γ-cyclodextrins

The steady state and time-resolved fluorescence study of 2-amino-4,6-dimethyl pyrimidine (ADMP) have been studied in aqueous solution of alpha- and gamma-cyclodextrins (CDs). In the presence of CDs, the fluorescence spectra of ADMP point out an enhancement of the emission without significant shift. The experimental data show the presence of only one kind of complex for ADMP in alpha- and gamma-CDs. Although, ADMP partially included within the interior CD cavities, it encapsulated inside the gamma-CD cavity more deeply, compared with the alpha-CD. The results also revealed that the polar amino group along with the endocyclic nitrogen remains located near the aqueous environment. (C) 2002 Elsevier Science BX All rights reserved.