Presence of sialic acid in N-linked oligosaccharide chains and O-linked N-acetylglucosamine in cruzipain, the major cysteine proteinase of Trypanosoma cruzi

被引：9

作者：

Barboza, M

Duschak, VG

Cazzulo, JJ

de Lederkremer, RM

Couto, AS ^{[1
]}

机构：

[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, CIHIDECAR, CONICET,Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina

[2] Univ Nacl Gral San Martin, Inst Invest Biotecnol, RA-1650 Buenos Aires, DF, Argentina

来源：

MOLECULAR AND BIOCHEMICAL PARASITOLOGY | 2003年 / 126卷 / 02期

关键词：

Trypanosoma cruzi; sialic acid; cruzipain; O-N-acetyl-D-glucosamine;

D O I：

10.1016/S0166-6851(02)00287-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：293 / 296

页数：4

共 20 条

[1] The mucin-like glycoprotein super-family of Trypanosoma cruzi:: structure and biological roles [J].

Acosta-Serrano, A ;

Almeida, IC ;

Freitas, LH ;

Yoshida, N ;

Schenkman, S .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 114 (02) :143-150

[2]

Acosta-Serrano A., 1995, J BIOL CHEM, V270, P27244

[3]

Brooks DR, 2000, J CELL SCI, V113, P4035

[4]

Cazzulo J.J., 1995, ACTA CHIM SLOV, V42, P409

[5] AMINO-ACID AND CARBOHYDRATE-COMPOSITION OF A LYSOSOMAL CYSTEINE PROTEINASE FROM TRYPANOSOMA-CRUZI - ABSENCE OF PHOSPHORYLATED MANNOSE RESIDUES [J].

CAZZULO, JJ ;

HELLMAN, U ;

COUSO, R ;

PARODI, AJA .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1990, 38 (01) :41-48

[6] ON THE POSTTRANSLATIONAL MODIFICATIONS AT THE C-TERMINAL DOMAIN OF THE MAJOR CYSTEINE PROTEINASE (CRUZIPAIN) FROM TRYPANOSOMA-CRUZI [J].

CAZZULO, JJ ;

MARTINEZ, J ;

PARODI, AJA ;

WERNSTEDT, C ;

HELLMAN, U .

FEMS MICROBIOLOGY LETTERS, 1992, 100 (1-3) :411-416

[7] The major cysteine proteinase of Trypanosoma cruzi:: A valid target for chemotherapy of Chagas disease [J].

Cazzulo, JJ ;

Stoka, V ;

Turk, V .

CURRENT PHARMACEUTICAL DESIGN, 2001, 7 (12) :1143-1156

[8]

Coombs Graham H., 1997, P177

[9]

DECAZZULO BMF, 1994, FEMS MICROBIOL LETT, V124, P81

[10] Functional diversity in the trans-sialidase and mucin families in Trypanosoma cruzi [J].

Frasch, ACC .

PARASITOLOGY TODAY, 2000, 16 (07) :282-286

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