Genetic epidemiology of the Mitsuda reaction in leprosy

被引：11

作者：

Feitosa, M

Krieger, H

Borecki, I

Beiguelman, B

Rao, DC

机构：

[1] UNIV WASHINGTON,SCH MED,DIV BIOSTAT,ST LOUIS,MO

[2] UNIV SAO PAULO,DEPT PARASITOL,BR-05508 SAO PAULO,BRAZIL

[3] UNIV ESTADUAL CAMPINAS,DEPT MED GENET,CAMPINAS,SP,BRAZIL

来源：

HUMAN HEREDITY | 1996年 / 46卷 / 01期

关键词：

Mitsuda reaction; leprosy; segregation analysis; genetic epidemiology;

D O I：

10.1159/000154322

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

This study comprised 544 nuclear families with 2,935 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (chi(1)(2) = 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (chi(3)(2) = 0.07 - 0.0 = 0.07, p > 0.99; chi(2)(2) = 198.28 - 0.0 = 198.28, p < 0.0001).

引用

页码：32 / 35

页数：4

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