Trace Analysis of Bromate in Potato Snacks Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry

被引：11

作者：

Arias, Francisco ^{[1
]}

Li, Lijuan ^{[1
]}

Huggins, Thomas G. ^{[1
]}

Keller, Paul R. ^{[1
]}

Suchanek, Paula M. ^{[1
]}

Wehmeyer, Kenneth R. ^{[1
]}

机构：

[1] Procter & Gamble Co, Global Analyt Capabil, Mason, OH 45040 USA

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2010年 / 58卷 / 14期

关键词：

Bromate; potato snacks; HPLC-MS/MS; stable isotope-labeled internal standard; HILIC; extraction; precision; accuracy; stability; specificity; recovery;

D O I：

10.1021/jf902732e

中图分类号：

S [农业科学];

学科分类号：

082806 [农业信息与电气工程];

摘要：

A simple, sensitive, and selective high-performance liquid chromatography tandem mass spectrometry (HPLC MS/MS) method in the negative-ion electrospray ionization (ESI(-)) mode was validated for the quantitation of bromate (BrO(3)(-)) in potato snacks. Ground snack specimens (similar to 0.5 g/sample) are spiked with Br(18)O(3)(-), stable-isotope labeled bromate internal standard (IS), and vortexed with a mixture of distilled/deionized water (dd water) and heptane. Subsequently, the specimens are centrifuged, and a small portion of the aqueous extract is isolated, diluted with dd water (1:4), and analyzed by HPLC MS/MS. The methodology has a quantitation range of 10-1000 ppb, an accuracy of 1.5-7.5%, and a precision of 5.2-13.4% across the concentration range.

引用

页码：8134 / 8138

页数：5

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