Translational mini-review series on vaccines: Monitoring of human papillomavirus vaccination

被引:41
作者
Dillner, J.
Arbyn, M.
Dillner, L.
机构
[1] Univ Hosp, Dept Clin Microbiol, WHO Global Reference Lab HPV Diag & Control, SE-20502 Malmo, Sweden
[2] Sci Inst Publ Hlth, Brussels, Belgium
[3] IARC, European Canc Network, Lyon, France
关键词
cancer prevention; surveillance; virus-like particles;
D O I
10.1111/j.1365-2249.2007.03384.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Persistent infection with oncogenic human papillomavirus (HPV) is a necessary cause of cervical cancer. Moreover, HPV type 16 (and to a lesser degree HPV type 18) is linked with more rare cancers, namely cancer of the vulva, vagina, penis, anus, oropharynx and larynx. Effective prophylactic vaccines have been developed. In this review, we briefly address immunological aspects of HPV infection and the results of HPV vaccination trials. Internationally standardized monitoring and evaluation of prophylactic HPV vaccination programmes will be essential for arriving at the most (cost-)effective strategies for cancer control.
引用
收藏
页码:199 / 207
页数:9
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