Efficient synthesis of 4-(2′-alkenyl)-2,5-dihydrofurans via PdCl2-catalyzed coupling-cyclization reaction of 2,3-allenols with allylic halides

被引：72

作者：

Ma, SM ^{[1
]}

Gao, WZ ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, Organomet Chem Lab, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 46期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/S0040-4039(00)01585-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

4-(2'-Alkenyl)-2, 5-dihydrofurans can be efficiently synthesized via the PdCl2-catalyzed coupling-cyclization of allylic halides with 2,3-allenols in DMA at rt in moderate to good yields. The regioselectivity is different from that of the Pd(0)-catalyzed coupling-cyclization of organic halides with 2,3-allenols. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：8933 / 8936

页数：4

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