Influence of the temperature on the enantioselectivity of the cobalt catalysed homo Diels-Alder reactions

被引：23

作者：

Pardigon, O

Tenaglia, A

Buono, G

机构：

[1] Univ Aix Marseille, CNRS, UMR 6516, Ecole Natl Super Synth Proc & Ingn Chim, F-13397 Marseille 20, France

[2] Ctr Rech Ingn & Technol, F-69053 Decines Charpieu, France

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 2003年 / 196卷 / 1-2期

关键词：

enantioselective; cobalt; cycloaddition; chiral P ligands; isoinversion principle;

D O I：

10.1016/S1381-1169(02)00646-5

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Depending on the variation of the temperature and on the nature of the substituent of alk-1-ynes 2, the enantioselectivity of the deltacyclene formation in the cobalt catalysed [2 + 2 + 2] cycloaddition of norbornadiene 1 and acetylenes 2, can be achieved with up to 98%. The best enantioselectivities observed around WC are in agreement with the Isoinversion principle (lip). (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：157 / 164

页数：8

共 34 条

[31] ENANTIOSELECTIVE SYNTHESES OF MONOFUNCTIONALIZED DELTACYCLENES USING A [COI2/ZN] CATALYTIC-SYSTEM [J].