New tissue engineering material copolymers of derivatives of cellulose and lactide: their synthesis and characterization

被引：25

作者：

Chen, DP ^{[1
]}

Sun, BQ ^{[1
]}

机构：

[1] Tsing Hua Univ, Dept Chem, Beijing 100084, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2000年 / 11卷 / 01期

基金：

中国国家自然科学基金;

关键词：

copolymers of hydroxyalkyl cellulose and lactide; ring-opening copolymerization;

D O I：

10.1016/S0928-4931(00)00131-4

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper reported the grafting copolymerization of L-lactide onto hydroxyethyl cellulose (PLA-HEC) or hydroxypropyl cellulose (PLA-HPC). They were obtained from ring-opening copolymerization of L-lactide with HEC or HPC in different mole ratios at 128 degrees C. Sn(Oct)(2) or LiCl was used as catalysts for the polymerization reaction. 400 MHz H-1 NMR analysis of products indicated that both Sn(Oct)(2) and LiCl could catalyze the reactions. Both PLA-HEC and PLA-HPC were biodegradable polymers with a good bioabsorbability, lack of toxicity, and were suitable for the use as tissue engineering materials. (C) 2000 Elsevier Science S.A. All rights reserved.

引用

页码：57 / 60

页数：4

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