The Influence of Perceptual Training on Working Memory in Older Adults

被引:161
作者
Berry, Anne S. [1 ,2 ]
Zanto, Theodore P. [1 ,2 ]
Clapp, Wesley C. [1 ,2 ]
Hardy, Joseph L. [3 ]
Delahunt, Peter B. [3 ]
Mahncke, Henry W. [3 ]
Gazzaley, Adam [1 ,2 ]
机构
[1] Univ Calif San Francisco, Dept Neurol, WM Keck Fdn Ctr Integrat Neurosci, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Physiol, WM Keck Fdn Ctr Integrat Neurosci, San Francisco, CA 94143 USA
[3] Posit Sci Corp, San Francisco, CA USA
来源
PLOS ONE | 2010年 / 5卷 / 07期
基金
美国国家卫生研究院;
关键词
VISUAL-EVOKED POTENTIALS; AGE-RELATED-CHANGES; MOTION ADAPTATION; SPATIAL-FREQUENCY; TIME-COURSE; ORIENTATION; DISCRIMINATION; SPECIFICITY; IMPROVEMENT; ATTENTION;
D O I
10.1371/journal.pone.0011537
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Normal aging is associated with a degradation of perceptual abilities and a decline in higher-level cognitive functions, notably working memory. To remediate age-related deficits, cognitive training programs are increasingly being developed. However, it is not yet definitively established if, and by what mechanisms, training ameliorates effects of cognitive aging. Furthermore, a major factor impeding the success of training programs is a frequent failure of training to transfer benefits to untrained abilities. Here, we offer the first evidence of direct transfer-of-benefits from perceptual discrimination training to working memory performance in older adults. Moreover, using electroencephalography to evaluate participants before and after training, we reveal neural evidence of functional plasticity in older adult brains, such that training-induced modifications in early visual processing during stimulus encoding predict working memory accuracy improvements. These findings demonstrate the strength of the perceptual discrimination training approach by offering clear psychophysical evidence of transfer-of-benefit and a neural mechanism underlying cognitive improvement.
引用
收藏
页数:8
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