Directed ortho metalation -: Cross coupling connections.: Total synthesis of Amaryllidaceae alkaloids buflavine and 8-O-demethylbuflavine

被引：14

作者：

Patil, PA

Snieckus, V ^{[1
]}

机构：

[1] Univ Waterloo, Guelph Waterloo Ctr Grad Work Chem, Waterloo, ON N2L 3G1, Canada

[2] CIDtech Res Inc, Mississauga, ON L5G 1H1, Canada

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 11期

基金：

加拿大自然科学与工程研究理事会;

关键词：

D O I：

10.1016/S0040-4039(98)00003-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The Amaryllidaceae alkaloids, buflavine (1) and 8-O-demethylbuflavine (2), have been synthesized by a sequence which highlights Directed ortho Metalation, Suzuki-Miyaura cross coupling, and intramolecular Peterson reactions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：1325 / 1326

页数：2

共 5 条

[1] ALPHA',ALPHA'-DISILYLATED TERTIARY BENZAMIDES AS DUAL ORTHO-CARBANION AND ALPHA'-CARBANION SYNTHONS - AMIDE PETERSON OLEFINATION ROUTES TO N-BENZOYL ENAMINES, ISOQUINOLINES, AND DIBENZAZOCINES [J].