Causes of death in HIV infection: the key determinant to define the clinical response to anti-HIV therapy

被引:30
作者
Mocroft, A
Gatell, J
Reiss, P
Ledergerber, B
Kirk, O
Vella, S
Blaxhult, A
Phillips, AN
Lundgren, J
机构
[1] Royal Free Centre for HIV Medicine, Dept. of Prim. Care and Pop. Sci., Roy. Free and Univ. Coll. Med. Sch., London
[2] Hospital Clinic Universitari, Barcelona
[3] Acad. Medisch Ctr. Univ. Amsterdam, Amsterdam
[4] University Hospital, Zürich
[5] Copenhagen HIV Program, Hvidovre Hospital, Copenhagen
[6] Istituto Superiore di Sanita, Rome
[7] Karolinska Hospital, Stockholm
关键词
D O I
10.1097/00002030-200411190-00018
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Studies have shown an increased risk of new AIDS/death among injecting drug users (IDU) starting highly active antiretroviral therapy (HAART). Of 3872 patients starting HAART in the EuroSIDA study, 819 were IDU (21.2%). During 14 769 person-years of follow-up, 499 patients progressed to new AIDS/death. Compared with homosexual individuals, IDU had an increased incidence of new AIDS/death, but only for non-HIV deaths. There is an urgent need to define and standardize causes of death in observational studies.
引用
收藏
页码:2333 / 2337
页数:5
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