Anti-aging protein SIRT1: A role in cervical cancer?

被引：10

作者：

Brooks, Christopher L.

Gu, Wei ^{[1
]}

机构：

[1] Columbia Univ, Inst Canc Genet, New York, NY 10032 USA

来源：

AGING-US | 2009年 / 1卷 / 03期

关键词：

p53; SIRT1; activation; transcription; small molecule; cell growth arrest; stability; cellular senescence; metabolism; aging; E6;

D O I：

10.18632/aging.100031

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：278 / 280

页数：3

共 17 条

[1] Phosphorylation of HuR by Chk2 regulates SIRT1 expression [J].

Abdelmohsen, Kotb ;

Pullmann, Rudolf, Jr. ;

Lai, Ashish ;

Kim, Hyeon Ho ;

Galban, Stefanie ;

Yang, Xiaoling ;

Blethrow, Justin D. ;

Walker, Mark ;

Shubert, Jonathan ;

Gillespie, David A. ;

Furneaux, Henry ;

Gorospe, Myriam .

MOLECULAR CELL, 2007, 25 (04) :543-557

[2] Resveratrol improves health and survival of mice on a high-calorie diet [J].

Baur, Joseph A. ;

Pearson, Kevin J. ;

Price, Nathan L. ;

Jamieson, Hamish A. ;

Lerin, Carles ;

Kalra, Avash ;

Prabhu, Vinayakumar V. ;

Allard, Joanne S. ;

Lopez-Lluch, Guillermo ;

Lewis, Kaitlyn ;

Pistell, Paul J. ;

Poosala, Suresh ;

Becker, Kevin G. ;

Boss, Olivier ;

Gwinn, Dana ;

Wang, Mingyi ;

Ramaswamy, Sharan ;

Fishbein, Kenneth W. ;

Spencer, Richard G. ;

Lakatta, Edward G. ;

Le Couteur, David ;

Shaw, Reuben J. ;

Navas, Placido ;

Puigserver, Pere ;

Ingram, Donald K. ;

de Cabo, Rafael ;

Sinclair, David A. .

NATURE, 2006, 444 (7117) :337-342

[3] How does SIRT1 affect metabolism, senescence and cancer? [J].

Brooks, Christopher L. ;

Gu, Wei .

NATURE REVIEWS CANCER, 2009, 9 (02) :123-128

[4] Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase [J].

Brunet, A ;

Sweeney, LB ;

Sturgill, JF ;

Chua, KF ;

Greer, PL ;

Lin, YX ;

Tran, H ;

Ross, SE ;

Mostoslavsky, R ;

Cohen, HY ;

Hu, LS ;

Cheng, HL ;

Jedrychowski, MP ;

Gygi, SP ;

Sinclair, DA ;

Alt, FW ;

Greenberg, ME .

SCIENCE, 2004, 303 (5666) :2011-2015

[5] The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth [J].

Firestein, Ron ;

Blander, Gil ;

Michan, Shaday ;

Oberdoerffer, Philipp ;

Ogino, Shuji ;

Campbell, Jennifer ;

Bhimavarapu, Anupama ;

Luikenhuis, Sandra ;

de Cabo, Rafael ;

Fuchs, Charles ;

Hahn, William C. ;

Guarente, Leonard P. ;

Sinclair, David A. .

PLOS ONE, 2008, 3 (04)

[6] Cancer-specific functions of SIRT1 enable human epithelial cancer cell growth and survival [J].

Ford, J ;

Jiang, M ;

Milner, J .

CANCER RESEARCH, 2005, 65 (22) :10457-10463

[7] VIRUSES IN HUMAN CANCERS [J].

HAUSEN, HZ .

SCIENCE, 1991, 254 (5035) :1167-1173

[8] INTEGRATION OF HUMAN PAPILLOMAVIRUS TYPE-16 DNA INTO THE HUMAN GENOME LEADS TO INCREASED STABILITY OF E6 AND E7 MESSENGER-RNAS - IMPLICATIONS FOR CERVICAL CARCINOGENESIS [J].

JEON, S ;

LAMBERT, PF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (05) :1654-1658

[9] Selective silencing of viral gene expression in HPV-positive human cervical carcinoma cells treated with siRNA, a primer of RNA interference [J].

Jiang, M ;

Milner, J .

ONCOGENE, 2002, 21 (39) :6041-6048

[10] The common mechanisms of transformation by the small DNA tumor viruses: The inactivation of tumor suppressor gene products: p53 [J].

Levine, Arnold J. .

VIROLOGY, 2009, 384 (02) :285-293

← 1 2 →