Ultrastructural changes in osteocytes in microgravity conditions

被引：52

作者：

Rodionova, NV ^{[1
]}

Oganov, VS

Zolotova, NV

机构：

[1] Ukrainian Acad Sci, Schmalhauzen Inst Zool, Kiev, Ukraine

[2] Inst Biol & Med Problems, RF SRC, Moscow, Russia

来源：

SPACE LIFE SCIENCES: BIOLOGICAL RESEARCH AND SPACE RADIATION | 2002年 / 30卷 / 04期

关键词：

D O I：

10.1016/S0273-1177(02)00393-9

中图分类号：

V [航空、航天];

学科分类号：

08 [工学]; 0825 [航空宇航科学与技术];

摘要：

We examined the histology and morphometry of biosamples (biopsies) of the iliac crest of monkeys, flown 14 days aboard the "Bion-11", using electron microscopy. We found, that some young osteocytes take part in the activization of collagen protein biosynthesis in the adaptive remodeling process of the bone tissue to microgravity conditions. Osteocyte lacunae filled with collagen fibrils; this correlates with fibrotic osteoblast reorganization in such zones. The osteolytic activity in mature osteocytes is intensified. As a result of osteocyte destruction, the quantity of empty osteocytic lacunae in the bone tissue increases. (C) 2002 COSPAR. Published by Elsevier Science Ltd. All rights reserved.

引用

页码：765 / 770

页数：6

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