New methods in combinatorial chemistry - robotics and parallel synthesis

被引：42

作者：

Cargill, JF

Lebl, M

机构：

[1] Ontogen Corp, Carlsbad, CA 92009 USA

[2] Trega Biosci Inc, San Diego, CA 92121 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1997年 / 1卷 / 01期

关键词：

D O I：

10.1016/S1367-5931(97)80110-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Technological advances in the automation of parallel synthesis are following the model set by the semiconductor industry: miniaturization, increasing speed, lower costs. Recent work includes preparation of high-density reaction blocks, development of ink-jet dispensing to polypropylene sheets and synthesis inside customized microchips.

引用

页码：67 / 71

页数：5

共 28 条

[1] Bartak Z., 1994, Methods (Orlando), V6, P432, DOI 10.1006/meth.1994.1046
[2] Combinatorial peptide libraries: Robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry, and high-performance capillary electrophoresis techniques
Boutin, JA
Hennig, P
Lambert, PH
Bertin, S
Petit, L
Mahieu, JP
Serkiz, B
Volland, JP
Fauchere, JL
[J]. ANALYTICAL BIOCHEMISTRY, 1996, 234 (02) : 126 - 141
[3] Bunin BA, 1996, METHOD ENZYMOL, V267, P448
[4] Cargill JF, 1996, LAB ROBOTICS AUTOMAT, V8, P139, DOI 10.1002/(SICI)1098-2728(1996)8:3<139::AID-LRA1>3.0.CO
[5] 2-1
[6] CONWAY P, 1997, LAB AUT 97 C JAN 18
[7] DEWITT SHH, 1996, MOL DIVERSITY COMBIN, P207
[8] Inclusion volume solid-phase synthesis
Eichler, Jutta
Houghten, Richard A.
Lebl, Michal
[J]. JOURNAL OF PEPTIDE SCIENCE, 1996, 2 (04) : 240 - 244
[9] Figliozzi GM, 1996, METHOD ENZYMOL, V267, P437
[10] FLOYD C, 1996, P INT S LAB AUT ROB, P51

← 1 2 3 →