Detection of hydrogen-bond signature patterns in protein families

被引:6
作者
Prasad, T [1 ]
Prathima, MN [1 ]
Chandra, N [1 ]
机构
[1] Indian Inst Sci, Bioinformat Ctr, Supercomp Educ & Res Ctr, Bangalore 560012, Karnataka, India
关键词
D O I
10.1093/bioinformatics/19.1.167
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We have developed a WWW server, HBPRINT, for the identification of hydrogen-bond signature patterns in protein families from their structures. The server calculates (a) common hydrogen bonds between two structures (b) a hydrogen-bond fingerprint in a set of structural neighbours and (c) details of conserved hydrogen bonds. The server also enables the visualization of the hydrogen bond network comprising the signature pattern.
引用
收藏
页码:167 / 168
页数:2
相关论文
共 7 条
[1]   HYDROGEN-BONDING IN GLOBULAR-PROTEINS [J].
BAKER, EN ;
HUBBARD, RE .
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 1984, 44 (02) :97-179
[2]   Crystal structure of a dimeric mannose-specific agglutinin from garlic: Quaternary association and carbohydrate specificity [J].
Chandra, NR ;
Ramachandraiah, G ;
Bachhawat, K ;
Dam, TK ;
Surolia, A ;
Vijayan, M .
JOURNAL OF MOLECULAR BIOLOGY, 1999, 285 (03) :1157-1168
[3]   Mapping the protein universe [J].
Holm, L ;
Sander, C .
SCIENCE, 1996, 273 (5275) :595-602
[4]   DALI - A NETWORK TOOL FOR PROTEIN-STRUCTURE COMPARISON [J].
HOLM, L ;
SANDER, C .
TRENDS IN BIOCHEMICAL SCIENCES, 1995, 20 (11) :478-480
[5]   Errors in protein structures [J].
Hooft, RWW ;
Vriend, G ;
Sander, C ;
Abola, EE .
NATURE, 1996, 381 (6580) :272-272
[6]   LIGPLOT - A PROGRAM TO GENERATE SCHEMATIC DIAGRAMS OF PROTEIN LIGAND INTERACTIONS [J].
WALLACE, AC ;
LASKOWSKI, RA ;
THORNTON, JM .
PROTEIN ENGINEERING, 1995, 8 (02) :127-134
[7]   More hydrogen bonds for the (structural) biologist [J].
Weiss, MS ;
Brandl, M ;
Sühnel, J ;
Pal, D ;
Hilgenfeld, R .
TRENDS IN BIOCHEMICAL SCIENCES, 2001, 26 (09) :521-523