In vitro DNA-based predator-prey system with oscillatory kinetics

被引：21

作者：

Ackermann, J ^{[1
]}

Wlotzka, B ^{[1
]}

McCaskill, JS ^{[1
]}

机构：

[1] Inst Mol Biotechnol, D-07745 Jena, Germany

来源：

BULLETIN OF MATHEMATICAL BIOLOGY | 1998年 / 60卷 / 02期

关键词：

D O I：

10.1006/bulm.1997.0001

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A coupled system of two isothermal in vitro DNA/RNA amplification reactions using different primers is modeled kinetically with realistic rate parameters and shown to exhibit oscillatory behavior in a flow reactor. One of the two isothermal amplification reactions acts as a predator of the other, the prey. The mechanism of the oscillatory behavior is analyzed in terms of a hierarchy of kinetic models. The work provides an insight into the choice of parameters for experiments. The latter are important in providing detailed insight into the complex processes of ecological interactions and their evolution. (C) 1998 Society for Mathematical Biology.

引用

页码：329 / 354

页数：26

共 34 条

[1] KINETICS OF RNA REPLICATION - PLUS-MINUS ASYMMETRY AND DOUBLE-STRAND FORMATION [J].