Effects of calcitonin on subchondral trabecular bone changes and on osteoarthritic cartilage lesions after acute anterior cruciate ligament deficiency

被引：68

作者：

Behets, C

Williams, JM

Chappard, D

Devogelaer, JP

Manicourt, DH ^{[1
]}

机构：

[1] Univ Catholique Louvain, Dept Anat, B-1200 Brussels, Belgium

[2] Rush Presbyterian St Lukes Med Ctr, Rush Med Coll, Dept Anat, Chicago, IL 60612 USA

[3] Univ Angers, INSERM, EMI 0335, Angers, France

[4] Univ Catholique Louvain, St Lukes Univ Hosp, Dept Rheumatol, B-1200 Brussels, Belgium

[5] Univ Catholique Louvain, ICP Christian Duve Inst Cellular Pathol, B-1200 Brussels, Belgium

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2004年 / 19卷 / 11期

关键词：

subchondral cancellous bone; osteopenia; osteoarthritis; salmon calcitonin; articular cartilage; pQCT;

D O I：

10.1359/JBMR.040609

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Because SBM may contribute to cartilage breakdown in OA, experimental OA was induced in dogs by transecting the anterior cruciate ligament of the knee and treating with either CT or a placebo. CT significantly reduced both SBM and cartilage lesions. This study supports the use of CT in the treatment of canine experimental OA.

引用

页码：1821 / 1826

页数：6

共 34 条

[1]

Early regional adaptation of periarticular bone mineral density after anterior cruciate ligament injury [J].