Layered γ-zirconium phosphate a new matrix for immobilization of hemoglobin

被引：11

作者：

Geng, LN ^{[1
]}

Li, N ^{[1
]}

Dai, N ^{[1
]}

Wen, XF ^{[1
]}

Zhao, FL ^{[1
]}

Li, KA ^{[1
]}

机构：

[1] Peking Univ, Coll Chem & Mol Engn, Dept Biol Chem, Beijing 100871, Peoples R China

来源：

COLLOIDS AND SURFACES B-BIOINTERFACES | 2003年 / 29卷 / 01期

基金：

中国国家自然科学基金;

关键词：

layered zirconium phosphate; intercalation; hemoglobin; immobilization;

D O I：

10.1016/S0927-7765(02)00182-0

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

Using layered gamma-zirconium phosphate (gamma-ZrP) for preparation of immobilized hemoglobin (Hb) was investigated. We discussed the effects of pH, ionic strength and concentration of amines on the intercalation and immobilization behaviors. The adsorption, desorption, catalytic activity, thermal stability of the inorganic solid-protein nanocomposites were also studied. This fundamental research was carried out aiming at comparing the influence of different surface properties on the Hb immobilization after gamma-ZrP has been pre-intercalated with different kinds of amine or without amine. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：81 / 88

页数：8

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