Predominance of SHV-5 β-lactamase in enteric bacteria causing community-acquired urinary tract infections in Bosnia and Herzegovina

被引:7
作者
Uzunovic-Kamberovic, S.
Bedenic, B.
Vranes, J.
机构
[1] Cantonal Publ Hlth Inst Zenica, Lab Clin & Sanit Microbiol Zenica, Zenica, Bosnia & Herceg
[2] Univ Zagreb, Dept Microbiol, Sch Med, Zagreb 41000, Croatia
关键词
ceftazidime; extended-spectrum beta-lactamases; Escherichia coli; Klebsiella pneumoniae; resistance; SHV-5;
D O I
10.1111/j.1469-0691.2007.01747.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
The beta-lactamases produced by 14 non-duplicate Klebsiella pneumoniae isolates and five Escherichia coli isolates from urine samples obtained from outpatients were characterised by isoelectric focusing, substrate profile determination, PCR and sequencing of bla(SHV) genes. Three E. coli A15 R+ transconjugants were identified as isolates that produced SHV-5 beta-lactamase. This report is the first description of SHV-5 beta-lactamase among community isolates. Since the isolates showed distinct pulsed-field gel electrophoresis patterns, it was concluded that there was no clonal spread of bla(TEM) and bla(SHV) genes, and that dissemination of the bla(TEM) and bla(SHV) genes was the result of exchange of plasmids among different clones.
引用
收藏
页码:820 / 823
页数:4
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