A simple, convenient and expeditious approach to cineol

被引：16

作者：

Bugarcic, ZM ^{[1
]}

Dunkic, JD ^{[1
]}

Mojsilovic, BM ^{[1
]}

机构：

[1] Univ Kragujevac, Fac Sci, Dept Chem, Radoja Domanovica 12,POB 60, YU-34000 Kragujevac, Serbia Monteneg

来源：

HETEROATOM CHEMISTRY | 2004年 / 15卷 / 06期

关键词：

D O I：

10.1002/hc.20044

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A convenient two-step protocol preparation of cineol (1-isopropyl-4-methyl-7-oxabicyclo-[2,2,1]heptane) from alpha-terpineol (p-menth-1-en-8-ol) is reported. The phenylselenoetherification of alpha-terpineol with PhSeX (X = Cl, Br, I) as a key step is described. alpha-Terpineol reacts with PhSeX to form the corresponding phenylselenoether in short reaction time and in quantitative yield. A subsequent reduction with Bu3SnH to cineol proceeds in high yield (98%) (C) 2004 Wiley Periodicals, Inc.

引用

页码：468 / 470

页数：3

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